Senior Chemical Engineer | Nankai University | China
Dr. Dazhen Xu is a distinguished researcher at Nankai University, Tianjin, China, specializing in organic synthesis, catalysis, and radical-mediated transformations. With 47 peer-reviewed publications and over 1,231 citations, Dr. Xu has established a notable presence in the field of synthetic and organometallic chemistry. His work primarily focuses on developing innovative, sustainable, and atom-economical methodologies for the construction of complex organic molecules, particularly through metal-catalyzed and metal-free multicomponent reactions. Recent studies highlight his group’s advancements in iron- and copper-mediated transformations, including Markovnikov-selective radical hydrothiolation of alkenes, oxidative arylation and hydroxylation of indolin-2-ones, and bromocyclization of olefinic amides, which contribute significantly to green chemistry and pharmaceutical synthesis. Dr. Xu’s research integrates mechanistic insight with practical synthetic utility, leading to scalable, cost-effective protocols that minimize environmental impact. His collaborations with over 70 co-authors reflect a strong interdisciplinary approach, bridging academic research and industrial application across catalysis, materials, and medicinal chemistry. With an h-index of 23, Dr. Xu’s publications have gained international recognition for their methodological innovation and relevance to sustainable chemical processes. His contributions not only advance the frontiers of organic chemistry but also align with global goals for environmentally benign synthesis, influencing future directions in both academic research and industrial innovation.
Profiles: Scopus | ORCID
Featured Publications
1. Wang, Y.-N., Jia, H., Yao, L., Chen, Y., Liu, H.-L., Liang, F., … Xu, D.-Z. (2025). Bifunctional iron-mediated multicomponent Markovnikov-selective radical hydrothiolation of alkenes. Organic Chemistry Frontiers, 12, 4462-4468.
2. Li, T.-Y., Xu, L.-L., Wu, D.-Q., Liu, J.-J., Yang, Y., Miao, Z., … Xu, D.-Z. (2025). Copper-Catalyzed Oxidative Arylation and Hydroxylation of Indolin-2-ones for Direct Construction of Tetrasubstituted Carbon Centers. Journal of Organic Chemistry, 90(2), 960-970.
Cited by: 1
3. Xu, L.-L., Wang, S., Sun, J., Zhang, R., Tong, J., … Xu, D.-Z. (2024). Facile access to S-aryl/alkyl dithiocarbamates via a three-component reaction under metal-free conditions. Organic & Biomolecular Chemistry, 22, 7702.
Cited by: 1
4. Zhao, T.-T., Bian, Q., Zhao, Y.-W., Xu, L.-L., Xu, D.-Z., & Zhao, W.-G. (2024). Iron-Mediated Bromocyclization of Olefinic Amides for the Synthesis of Bromobenzoxazines. Synthesis, 56, 2993-3000.
Cited by: 3
Dr. Dazhen Xu’s pioneering research in sustainable catalysis and radical chemistry is transforming the way complex molecules are synthesized, promoting greener and more efficient chemical manufacturing. His vision is to integrate eco-conscious innovation with high-impact synthetic strategies, advancing both scientific knowledge and the global transition toward sustainable chemical industries.
